"You can't help getting older, but you don't have to get old." said George Burns who lived well into his nineties. Aging, unfortunately, is a part of life. How we age is now, facilely becoming a fate we place in our own hands. On the predictions of Francis Bacon, Rene Descartes, and Benjamin Franklin, the science of anti-aging has come to be an art. Unfortunately less than 1% of Md's and 1/2% of nurses have received training dealing with the extra needs of older adults.
Instead of searching for the ever illusive "fountain of youth", millions of Americans are slowing their own biological clocks with the proven methods of today's latest research. While genetic make-up and the world's environmental influences will still affect the aging process, never before have so many had the opportunity to fight father time and extend their life.
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Aging used to be clear and while some degree of aging still is, the data found on these and the following pages, offers some understanding to the many spectacular, breakthroughs in the science of anti-aging.
Rising life expectancy means members of the huge baby boom generation who are nearing old age, can look forward to more golden years than their parents. With aging arresting is key. Start your own journey to a younger feeling and healthier you.
The Key to Anti-Aging: Telomeres
Robert Browning wrote, "Grow old with me, the best is yet to be" more than 100 years ago. At that time, it may have well been very true. Even twenty, or ten, years ago that still held true. As the dawn rises on a new millennium spectacular, new advances in science and technology are occurring along with a shift in group consciousness, make it possible to now operate the aging process.
Over the recorded existence of man the median human life span has increased. This growth is owed to improvements in medical care, along with the use of antibiotics, improvements in housing, study and sanitation. However, there appears to be a maximum, or fixed, end point. recent investigate reports have indicated that the aging process itself could certainly be modified. Evidence for this comes from the isolation of "longevity genes", as well as the ensue on cell longevity by modification of the ends of the chromosomes (the telomeres), elimination of treacherous free radicals, glucose cross-linking of proteins, and the ensue of hormones and protective enzymes.
Human cells have a microscopic life span. In a test tube a normal human cell will divide about 50 times and then dies of old age. This seems to put a ceiling on the human life span. The culprits are telomeres-minute units at the end of the Dna chain. Each time a cell divides it must double its Dna. This process results in the shortening of the telomeres. After about 50 such replications the telomeres are gone, and the cell loses its quality to divide.
Howard Cooke of the medical investigate Council in Edinburgh, documented the first association in the middle of aging and telomeres. He noticed that the telomeres in reproductive cells were longer than those in shorter-lived somatic cells (the kind found in muscle, skin and nerve tissue). He recommend that ever-shortening telomeres might settle a cells life-span. In other words, he proposed that the telomere length offered a clock for telling a cell's longevity.
In a barrage of papers published over the last few years, researchers have shown that the telomerase gene can be activated in human cells, and that it does extend cell life. The initial amelioration was a record in the August 15, 1997, issue of Science. A group headed by Nobel laureate Thomas Cech, of the University of Colorado at Boulder, and colleagues at Geron Corporation, had isolated the human gene for a catalytic protein called telomerase reverse transcriptase (hTrt).
hTrt is only present in immortal cells, whereas the gene for telomerase is pre-sent in all cells. Htrt serves to fuse the repeating sequences of Dna to the chromosomes, thereby lengthening the telomeres. Proof that introduction of the hTrt gene into mortal cells would cause them to produce active telomerase was offered in the December 1, 1997, issue of Nature Genetics by the Geron group, in a collaboration with researchers from the University of Texas Southwestern medical center in Dallas.
Telomerase is a rarely-expressed enzyme believed to play a key role in the regulation of cell life span, functioning as part of a molecular clock of cell aging. Its absence imparts mortality to some cells and its nearnessy imparts replicative immortality to others.
"Reconstituting telomerase activity, especially in normal human cells, is a major milestone in telomerase biology that has comprehensive implications for the treatment of cancer and age-related diseases," said Jerry Shay, Ph.D., professor of cell biology at the University of Texas Southwestern medical center in Dallas.
"Since cell senescence contributes to age-related disorders and limits the efficacy of cell and gene therapies, the quality to extend the life span of normal cells would have broad therapeutic and market impact," stated Ronald Eastman, Geron's President and Chief menagerial Officer.
While the ensue this will have on the normal group is still yet undetermined, agreeing to Jerry Shay Ph.D., "Telomerase will allow us to take a person's own cells, manipulate and rejuvenate them, and give them back to the same patient. The rejuvenated cells could help grow new skin for burn victims and cure diseases caused by the failure of aging cells to divide, such as macular degeneration."
For the first time in history, operate of the aging process lies in the hands of mankind. How we will talk to that challenge is still an open question. But one thing is certain, for the generations just being born, living to be 100 will be routine.
The extreme Spare Part: Stem Cells
In July 1997, a researcher from Johns Hopkins medical establish announced that he had human stem cells growing in a lab dish. That announcement, following close on the heels of Dolly (the cloned sheep), represents an additional one step towards a brave new world of high-tech reproduction. The most engaging leap in this race is that while Dolly grew into a very normal finding sheep, the stem cells in professor John Gearhart's petri dish, should be able to establish into any cell in the human body.
Umbilical cord blood stem cells are thought about a medical breakthrough and have been in the news recently in terms of advancements in health, science, transplant medicine, women's condition and disease treatments such as Hodgkin's disease, lymphoma and leukemia. Time to come applications and investigate are in areas of gene therapy and autoimmune diseases; rheumatoid arthritis, multiple sclerosis, lupus and other immune theory disorders.
Gearhart says, "We clearly had evidence for human stem cells. They've been able to differentiate into some tissue types in a dish." Move over Dolly, stem cells are truly the extreme spare part.
Sleep: one of the most prominent functions
"Early to bed, early to rise, makes a man, healthy, wealthy and wise," states the nursery rhyme, but for many older Americans, "early to rise" may be a familiar, although troubling, part of their daily routine.
One of the most tasteless complaints among the aging is that of sleep difficulty. In a study completed by the National establish on Aging, of 9000 persons aged 65 years and older, over one half of the men and women reported at least one lasting sleep complaint. Typical sleep problems as we age comprise strangeness falling asleep, maintaining sleep, early morning awakening, and immoderate daytime sleepiness.
Melatonin secretion is complicated in physiologic sleep onset. We produce melatonin abundantly until puberty, and then it declines steadily into old age, thus causing the related sleep deficiencies.
Chronic sleep loss, agreeing to Dr. Eve Van Cauter, may speed the onset or growth the severity of age related conditions such as type 2 diabetes, high blood pressure, obesity, and memory loss.
Several generalizations can be made regarding aging and sleep characteristics. Compared with younger persons, as we age we tend to accomplish less total nighttime sleep. Nevertheless, it cannot be assumed that older habitancy wish less sleep. Overall, the sleep-wake cycle in the elderly is fragmented, thus causing them to have more nighttime arousal's and awakenings. Although a mild deterioration in sleep quality may be a normal part of the aging process, complaints of significantly disrupted nighttime sleep, or impaired daytime functioning because of immoderate sleepiness, must be addressed.
The Obesity Epidemic
Since 1991 the United States has seen a drastic growth in the whole of obese citizens, agreeing to a record in an issue of the Journal of the American medical Association. The study's author wrote, "the obesity epidemic has spread with the speed and dispersion characteristic of a communicable disease epidemic".
A decade ago 1 in every 4 Americans was seriously overweight. Today it is 1 in 3, and climbing. Obesity is a disease that affects at least 70 million Americans; more than one-third of all adults and one in every five children. Many of today's obese are elderly. As many as 3 million of Americans aged 65 and over have weight problems. Each year, obesity causes at least 300,000 deaths and costs the country more than 0 billion.
In today's community the terms obesity and overweight are often interchanged in daily conversations, but they mean two distinct weight states. The term obesity refers to an excess of body fat enough to impair health, function or longevity. Obesity is most often defined as being 20% or more over your ideal body weight. Using this definition, obesity affects an estimated 70 million Americans. Obesity is a tasteless condition, which can have profoundly negative condition and group consequences, and is thought about a serious disease that has been related to shortened life expectancy. agreeing to C. Everett Koop, old Surgeon normal of the United States, obesity is the second prominent cause of preventable death in America today.
Obesity is an independent risk factor or aggravating agent for more than 30 medical conditions along with diabetes, bad knees, high blood pressure, hardening of the arteries, and increased blood cholesterol.
How to form your B.M.I. Index
The following table of Body Mass Index (Bmi) will help you settle your own Bmi. Bmi is calculated by taking a person's weight in kg (kg=pounds/2.2) and dividing by the persons's height in meters squared (meters=inches x 0.0254).
Find the row that most intimately matches your weight in pounds. Read over the row until it crosses the column that most intimately matches your height in feet and inches. If you find yourself in a cell that is dark red (Bmi Greater or equal to 30 kg/m2), then you may be a candidate for weight discount therapy. If the cell is pink (Bmi greater or equal to 27 kg/m2 and less than 20 kg/m2) then you may be a candidate if you have other risk factors, as mentioned in the obesity article.
Bmi 5'0" 5'3" 5'6" 5'9" 6'0" 6'3"
140# 27 25 23 21 19 18
150# 29 27 24 22 20 19
160# 31 28 26 24 22 20
170# 33 30 28 25 23 21
180# 35 32 29 27 25 23
190# 37 34 31 28 26 24
200# 39 36 32 30 27 25
210# 41 37 34 31 29 26
220# 43 39 36 33 30 28
230# 45 41 37 34 31 29
240# 47 43 39 36 33 30
250# 49 44 40 37 34 31
How Fat Affects Us
* Lungs - In overweight habitancy an increased body volume must be supplied with oxygen by lungs that have not correspondingly increased in size. In addition, the presences of thick pads of fat in the abdomen restricts breathing. Anesthetic risk in increased in overweight patients. Being overweight can be a extra problem for asthmatics.
* Diabetes - Diabetes is more tasteless in overweight patients than in patients of normal weight. In one group of studies, 70-80% of diabetics had a history of obesity. When an overweight diabetic loses weight, the diabetes often improves.
* fertilization - being overwight can be a factor in producing difficult and prolonged labor due to abnormal positioning of the fetus. This can cause fetel distress, which, in turn, may complicate labor and delivery. In addition, severely overweight women have more difficult pregnancies and an increased occurrence of maternal and child deaths.
* Sugery - Surgical procedures are more difficult in overweight individuals due to the very bulk of the adipose tissues.
* Hernia - clear types of hernias, engaging displacement of the upper part of the stomach into the chest cavity, are more prevalent in overweight individuals than in those of normal weight.
* Joint-Disease - A vicious cycle is set up in overweight patients with arthiritis of the hip, knees, or feet, or in those who suffer from a ruptured intervertebral disc. Increased weight leads to greater wear and tear on these joints, which may come to be more angry and painful. The increased pain forces the inpatient to come to be less and less active, thereby favoring supplementary gain in weight.
* Adipose Tissue - Adipose (fat) tissue is composed of extremely elastic cells that comprise varying amounts of fatty deposits acquired via the bloodstream. Adipose tissue occurs throughout the body, face vital organs and muscles. Overweight habitancy have immoderate fat deposits on virtually all soft organs and tissues. The whole of fat cells present, and the whole of fat they contain, determines the degree of overweight.
* Blood Pressure - High blood pressure (hypertension) occurs more oftentimes in overweight people. Since hypertension can ensue in varying degrees of damage to the brain (stroke) and kidneys (degeneration), as well as the heart, it is important that hypertensive overweight patients lose weight.
* Heart - Because the heart must provide nutrients to all tissues of the body, the greater the body mass, the greater the strain on the heart. Overweight habitancy have a higher incidence of heart disease, the nations whole oen killer.
* Atherosclerosis - Atherosclerosis is the deposit of fatty material on the lining of the arterial wall. It can ensue in the rupture of the blood vessel or in narrowing of these vessels, which may lead to stroke or heart attack. Studies show that there is a marked growth in the occurrence of atherosclerosis in overweight people.
* Gallbladder - a significantly higher incidence of gallbladder disease is observed in overweight patients than in those of normal weight. In one study, 88% of the patients operated on for gallstones were found to be overweight.
* The Omentum - the "pot bellied" appearance of many individuals is prmarily the ensue of fat accumulating within the abdominal cavity (omentum).
* Baby Fat - No type of fat, baby or otherwise, is cute. The fat cells produces by childhood weight-gain remain throughout life and can make it difficult to lose weight as an adult.
Nutrition For Life
As we coming the 21st century, there is even greater focus on the baby boom generation. Baby boomers are a key factor in the statistics that the elderly will comprise a much larger share of the population. agreeing to Food Insight, in 1980 one in ten persons were age 65 or older. By 2030, the 65 and older whole will be one in five. In the year 2011 the first "boomers" will reach age 65.
Most projections say the median age of death in the next century will climb to 84. Currently the median life span is 73 years. Due to the latest in anti-aging research, life spans are now being extended to ensure that the second 50 years are healthier, creating more quality and enjoyment
According to Ann W. Sorenson, Ph.D., condition science administrator at the National establish on Aging, "we don't have a good handle on nutrient execution for older people." Most experts agree that the dietary needs of habitancy in their 50s or 60s are distinct from habitancy in their 70s and 80s.
Irwin B. Rosenberg, M.D., stated "the challenge we face is to allege a higher degree of physiologic execution throughout the life cycle so that the individuals in our community are more independent, more mobile, more able to take care of themselves." Diet and cusine are going to be very prominent aspects of condition patterns in which there can be intervention.
Many lasting diseases that establish late in life can be related to earlier poor eating habits. Insufficient practice and calcium intake while adolescence and early adulthood significantly growth the risk of osteoporosis, which causes bones to be brittle, and crack or break. However, good diet in later years can lessen the effects of diseases such as osteoporosis, obesity, high blood pressure, heart disease, clear cancers, gastrointestinal problems and lasting under-nutrition.
Having a good diet in later years contributes to a higher quality of life, enabling older habitancy to allege their independence by lasting to accomplish basic daily activities such as bathing, dressing and eating. On the other hand poor cusine increases the rescue time from illness, increases the possibility of institutionalization, and creates poor quality of life.
The American Dietetic association states that, as you age, minerals are lost in your bones causing osteoporosis to develop. Bones break certainly and take longer time to heal. It can establish in any man or woman. There are some ways to safe and enlarge your bones, for example walking makes bones strong, calcium intake needs to be high, along with getting enough vitamin D. An record in Newsweek stated that among those at most risk for vitamin D deficiencies are the elderly, alcoholics, and habitancy living in sun-poor climates. Studies advise that vitamin D may also safe against cancer. Typically as we age we tend to get less exposure to the sun, causing reduced capacity for synthesis of vitamin D, which is important for proper calcium absorption.
For a variety of reasons, agreeing to Food Insight, the sense of taste and smell decline as we age. This is the ensue of disease, injury, drug treatments, as well as normal aging. Susan Schiffman, Ph.D. States that a discount of comprehensive quality of life is experienced, creating increased depression, stress, and poor nutrition. In extreme cases, older habitancy can come to be anorexic.
The U.S. Food and Drug administration states, chewing problems are also related with aging, causing habitancy to lack clear foods in their diets. Gastrointestinal disturbances, such as constipation, diarrhea, and heartburn, are also attributed to poor nutrition. Supplements are recommend to keep your body functioning properly. Straight through approved lifestyle, the degenerative biological changes related with old age can, in many cases, be arrested.
Poor cusine worsens the impact of lasting disease, reduces resistance to infections, slows healing, and increases use of the healthcare system. Nutrient density can be increased by nutritional supplements. Traditionally, pills and painful shots were your options. Using the idea of oral absorption, Straight through spray vitamins and nutraceuticals, today's technology has created a revolutionary, favorable alternative to maintaining enough levels of nutrients. Spray vitamins and nutraceuticals are up to 90 percent effective, allowing your body to acquire the important nutrients. Pills comprise fillers and binders. Such as talcum powder, yeast, starch, sugar, wax and shellac. In comparison to sprays, pills are only 10 to 50 percent effective.
How are pills made?
Makers of pills, tablets, or caplets have approved size molds for the precise size of their pill. It does not matter what the active ingredients are because the manufacturer will add fillers, binders, waxes, and other excipients to take up the space. A filler does nothing more than take-up volume. Some tasteless fillers are talcum powder, sugar, whey and yeast.
If a firm claims it does not use any of these tasteless fillers, then they certainly use dehydrogenated animal fat. They have to use something to fill up the space within the mold. Also they must use wax or some kind of binders to make the components stick together when they squeeze everything to make the pill.
The molds must be sprayed with a releasing agent which is an additional one form of wax or grease to allow the pill to drop out of the mold. Some tablets are coated with a shiny coating. This is ordinarily shellac-the same as used on wood floors and boats! Time issue capsules are made of a compound of shellac, fillers and 200 proof alcohol. There is a microscopic bit of active ingredient and fillers coated with the shellac/alcohol mixture. The division of alcohol controls the time the pill takes to dissolve in the stomach.
Normal tablets must meet U. S. Pharmacopeia (U.S.P.) standards. U.S.P. Standards wish that tablets must dissolve within 15 to 30 minutes once in your stomach. To test your tablets, place white vinegar in a dish or glass and drop in your pill. Check periodically. It should dissolve(disappear) within 15 to 30 minutes to meet U.S.P. Standards. If it doesn't, then you are paying a high price for fillers! You can keep this test up for 45 to 60 minutes, but if the pill is not dissolved by then, it can't possibly generate any advantage to your body.
What are By-Products?
By-products are the second-hand substances derived from an original product. Brewer's Yeast is a leftover in the making of beer, yeast is used to ferment the sugar. Many associates take these secondary products, put them in a white plastic bottle with some other ingredient like caffeine, and label them with sensational sounding names but what they certainly are is just waste products with microscopic nutritional value. Sure, they list the percentages of each component they can find, but dirt is high in mineral contents too. Would you pay money for dirt? It's hard to understand why some habitancy will pay a high price for secondhand products.Anti-Aging - Educate Yourself